Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.47 |
| ▸ | GSR | P00390 | 4/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746291 | 0.92 | TMEM97 (0.49) | TMEM97GSRNPY1RTDP1KCNH2 | |
| SCHEMBL4748253 | 0.86 | GSR (0.48) | TMEM97GSRNPY1RMC4RHTR1A | |
| SCHEMBL4748220 | 0.85 | GSR (0.48) | TMEM97GSRKCNH2MC4RHTR1A | |
| SCHEMBL4747565 | 0.85 | GSR (0.48) | TMEM97GSRHTR1AHTR7KDM4E | |
| SCHEMBL4744199 | 0.85 | KCNH2 (0.48) | TMEM97GSRNPY1RTDP1KCNH2 | |
| SCHEMBL4747148 | 0.84 | HRH3 (0.39) | MC4R | |
| SCHEMBL4747828 | 0.83 | GSR (0.45) | GSRKDM4EALDH1A1HPGD | |
| SCHEMBL4744200 | 0.78 | GSR (0.46) | GSRHTR1AHTR7KDM4EALDH1A1 | |
| SCHEMBL4743800 | 0.76 | HRH3 (0.38) | MC4R | |
| SCHEMBL4743759 | 0.75 | MPO (0.43) | GSRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |