Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748220 | 0.93 | GSR (0.48) | GSRALDH1A1KDM4EHPGDALOX5 | |
| SCHEMBL4743769 | 0.87 | LCK (0.41) | GSRALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL4743788 | 0.85 | GSR (0.51) | GSRALDH1A1KDM4EHPGDALOX5 | |
| SCHEMBL4748253 | 0.83 | GSR (0.48) | GSRALDH1A1KDM4EHPGDALOX5 | |
| SCHEMBL4747565 | 0.82 | GSR (0.48) | GSRALDH1A1KDM4EHPGDHTR1A | |
| SCHEMBL4744199 | 0.81 | KCNH2 (0.48) | GSRALDH1A1KDM4EHPGD | |
| SCHEMBL4744753 | 0.80 | ACP1 (0.40) | GSRMCHR1 | |
| SCHEMBL4744550 | 0.78 | TMEM97 (0.47) | GSRALDH1A1KDM4EHPGDHTR1A | |
| SCHEMBL4746265 | 0.77 | GSR (0.61) | GSRALDH1A1KDM4EHPGD | |
| SCHEMBL4746291 | 0.76 | TMEM97 (0.49) | GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |