Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747666 | 0.90 | DRD2 (0.46) | DRD2DRD4GRM2CACNA1GHTT | |
| SCHEMBL4747167 | 0.88 | DRD2 (0.44) | DRD2DRD4GRM2CACNA1GHTT | |
| SCHEMBL4744655 | 0.86 | DRD2 (0.46) | DRD2DRD4GRM2CACNA1GHTT | |
| SCHEMBL4748322 | 0.86 | CACNA1G (0.41) | DRD4CACNA1GHTTMEN1ALDH1A1 | |
| SCHEMBL4745089 | 0.86 | DRD2 (0.45) | DRD2DRD4GRM2CACNA1GHTT | |
| SCHEMBL4746757 | 0.86 | DRD2 (0.43) | DRD2DRD4GRM2CACNA1GHTT | |
| SCHEMBL4744996 | 0.85 | DRD2 (0.46) | DRD2DRD4GRM2CACNA1GHTT | |
| SCHEMBL4744949 | 0.85 | KMT2A (0.52) | DRD2DRD4GRM2CACNA1GHTT | |
| SCHEMBL4746781 | 0.84 | MEN1 (0.46) | DRD2DRD4GRM2CACNA1GHTT | |
| SCHEMBL4748316 | 0.84 | MEN1 (0.46) | DRD2DRD4GRM2CACNA1GHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |