SCHEMBL4748711

SCHEMBL4748711

Cc1cc(=O)n(-c2cccc([N+](=O)[O-])c2)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.57
GAA P10253 5/20 0.57
HPN P05981 1/20 0.51
KMT2A Q03164 8/20 0.50
MEN1 O00255 7/20 0.50
RAB9A P51151 2/20 0.50
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.50
ALDH1A1 P00352 5/20 0.49
KDM4E B2RXH2 4/20 0.49
HTT P42858 3/20 0.49
SCN2A Q99250 1/20 0.49
TDP1 Q9NUW8 2/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 2/20 0.47
ACHE P22303 1/20 0.47
LMNA P02545 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2435022 0.83 MAPT (0.61) MAPTGAAKMT2AMEN1RAB9A
SCHEMBL11478374 0.79 MAPT (0.48) MAPTGAAHPNKMT2AMEN1
SCHEMBL11203388 0.79 ALKBH5 (0.63) MAPTGAAHPNKMT2AMEN1
SCHEMBL11417170 0.79 MAPT (0.50) MAPTGAAKMT2AMEN1RAB9A
SCHEMBL5675303 0.78 ALKBH5 (0.65) MAPTGAAKMT2AMEN1POLB
SCHEMBL15124575 0.78 MAPT (0.54) MAPTGAAKMT2AMEN1RAB9A
SCHEMBL11776841 0.78 PDE4B (0.54) MAPTGAAKMT2AMEN1POLB
2-Amino-4-Nitrophenol SCHEMBL11023068 0.78 GAA (0.55) MAPTGAAKMT2AMEN1RAB9A
SCHEMBL4399573 0.77 MAPT (0.53) MAPTGAAKMT2AMEN1RAB9A
SCHEMBL4023307 0.76 MAPT (0.57) MAPTGAAKMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541299-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-07-30 US claimed
CN-114751862-B PMP derivative, synthesis method and application thereof in detection of monosaccharide 安徽中医药大学 2023-12-22 CN disclosed
CN-114751862-A PMP derivative, synthetic method and application in monosaccharide detection 安徽中医药大学 2022-07-15 CN disclosed
CN-102952158-A Triazine type siloxane surface modifier and preparation method thereof UNIV DALIAN TECH 2013-03-06 CN disclosed
WO-2008121861-A2 PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS XENON PHARMACEUTICALS INC. (CA) 2008-10-09 WO disclosed
US-6670387-B1 Thrombocytopenia; hydroxy-1-azo-naphthalene derivatives; 3-hydroxy-4-((2-hydroxy-1-naphthalenyl)azo-)-1-naphthalenesul fonic acid; promoters of thrombopoiesis and megakaryocytopoi esis; enhancing platelet production; agonizing TPO receptor SMITHKLINE BEECHAM CORPORATION 2003-12-30 US disclosed
EP-1156804-A4 THROMBOPOIETIN MIMETICS SMITHKLINE BEECHAM CORP (US) 2002-08-07 EP disclosed
EP-1156804-A1 THROMBOPOIETIN MIMETICS SMITHKLINE BEECHAM CORPORATION (US) 2001-11-28 EP disclosed
WO-2000035446-A1 THROMBOPOIETIN MIMETICS SMITHKLINE BEECHAM CORPORATION (US) 2000-06-22 WO disclosed
US-5578711-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-11-26 US disclosed
US-4221709-A Azo pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1980-09-09 US disclosed
US-4144231-A Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4143033-A WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4137228-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed
US-4122278-A INTERMEDIATES FOR DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-10-24 US disclosed
US-4101540-A USEFUL FOR DYEING ACRYLONITRILE POLYMERS OR ACID-MODIFIED POLYESTERS OR POLYAMIDES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-18 US disclosed
US-4097475-A FOR POLYESTERS AND BLENDS WITH CELLULOSE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-27 US disclosed
US-4083839-A Unsymmetrical mono sulfo containing 1:2 azo, azo chromium complex dyes CIBA-GEIGY CORPORATION (US) 1978-04-11 US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3970615-A Unsymmetrical mono-sulfo containing chromium complexes of azo dyes CIBA-GEIGY CORPORATION (US) 1976-07-20 US disclosed