Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecane SCHEMBL11373218 | 0.90 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL5675303 | 0.84 | ALKBH5 (0.65) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL486340 | 0.82 | ALDH1A1 (0.69) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL9150171 | 0.82 | ALDH1A1 (0.68) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL34121 | 0.82 | ALDH1A1 (0.68) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL5425653 | 0.82 | ALDH1A1 (0.68) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL7893151 | 0.81 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27912588 | 0.81 | ALKBH5 (0.61) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27912589 | 0.81 | ALDH1A1 (0.54) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL486408 | 0.80 | MAPT (0.71) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976488-A | COUPLER, EXTENDER, DISPERSION MEDIUM | MITA INDUSTRIAL COMPANY, LTD. (JA) | 1976-08-24 | — | — | US | claimed |
| WO-2024110326-A1 | USE OF YELLOW THERMOSTABLE METHINE DYES FOR DYEING PLASTICS | LANXESS DEUTSCHLAND GMBH (DE) | 2024-05-30 | — | — | WO | disclosed |
| US-8962623-B2 | Aminopyrazine compounds | LOCUS PHARMACEUTICALS, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140187529-A1 | AMINOPYRAZINE COMPOUNDS | LOCUS PHARMACEUTICALS, INC. (US) | 2014-07-03 | — | — | US | disclosed |
| CN-102952158-A | Triazine type siloxane surface modifier and preparation method thereof | UNIV DALIAN TECH | 2013-03-06 | — | — | CN | disclosed |
| WO-2012121939-A2 | AMINOPYRAZINE COMPOUNDS | LOCUS PHARMACEUTICALS, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| US-7513943-B2 | Yellow dye compound and ink composition comprising the same | EVERLIGHT USA, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20090056586-A1 | Yellow dye compound and ink composition comprising the same | EVERLIGHT USA, INC. (US) | 2009-03-05 | — | — | US | disclosed |
| EP-1213965-B1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2006-01-18 | — | — | EP | disclosed |
| US-6670387-B1 | Thrombocytopenia; hydroxy-1-azo-naphthalene derivatives; 3-hydroxy-4-((2-hydroxy-1-naphthalenyl)azo-)-1-naphthalenesul fonic acid; promoters of thrombopoiesis and megakaryocytopoi esis; enhancing platelet production; agonizing TPO receptor | SMITHKLINE BEECHAM CORPORATION | 2003-12-30 | — | — | US | disclosed |
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |
| US-4086223-A | Asymmetrical 1:2-chromium complex azo dyestuffs | CIBA-GEIGY AG (CH) | 1978-04-25 | — | — | US | disclosed |
| US-4083839-A | Unsymmetrical mono sulfo containing 1:2 azo, azo chromium complex dyes | CIBA-GEIGY CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |
| US-4029643-A | Chromium containing azo dyes | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1977-06-14 | — | — | US | disclosed |
| US-4011237-A | HETEROCYCLIC SUBSTITUTED CHROMENOPYRAZOLES | CIBA-GEIGY CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |
| US-3981730-A | HUE SEPARATION, POLYALKYLENE OXIDES, FATTY ACID DERIVATIVES | MITA INDUSTRIAL COMPANY, LTD. (JA) | 1976-09-21 | — | — | US | disclosed |
| US-3976488-A | COUPLER, EXTENDER, DISPERSION MEDIUM | MITA INDUSTRIAL COMPANY, LTD. (JA) | 1976-08-24 | — | — | US | disclosed |
| US-3971741-A | DISPERSION PIGMENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
| US-3944428-A | Alkaline curing corrugating adhesive | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |
| US-3933787-A | DYEING AND PRINTING PAPER | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090056586-A1 | Yellow dye compound and ink composition comprising the same | RB1, TYR, IK | MAPT 565/4885ALDH1A1 551/4885SMN1; SMN2 2806/4885 |
| US-20140187529-A1 | AMINOPYRAZINE COMPOUNDS | ITK, IL4I1, IL5 | MAPT 1970/4885ALDH1A1 800/4885SMN1; SMN2 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.