Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043699 | 0.92 | NPSR1 (0.49) | NPSR1POLBPPARGEPHX2MMP8 | |
| SCHEMBL6809652 | 0.88 | MMP8 (0.48) | NPSR1POLBPPARGEPHX2MMP8 | |
| SCHEMBL4750069 | 0.82 | CES2 (0.46) | NPSR1POLBMMP8KMT2AMEN1 | |
| SCHEMBL4749311 | 0.82 | MMP8 (0.47) | NPSR1PPARGEPHX2MMP8KMT2A | |
| SCHEMBL28147664 | 0.82 | NPSR1 (0.49) | NPSR1POLBPPARGEPHX2KMT2A | |
| SCHEMBL28464077 | 0.82 | MMP8 (0.50) | NPSR1POLBMMP8KMT2AMEN1 | |
| SCHEMBL2484700 | 0.81 | CES2 (0.56) | NPSR1POLBPPARGEPHX2KMT2A | |
| SCHEMBL6675458 | 0.81 | CES2 (0.56) | NPSR1POLBPPARGEPHX2KMT2A | |
| SCHEMBL9315410 | 0.81 | POLB (0.50) | NPSR1POLBPPARGEPHX2KMT2A | |
| SCHEMBL17634101 | 0.79 | NPSR1 (0.47) | NPSR1POLBPPARGEPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | disclosed |