Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904300 | 0.96 | PGR (0.34) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4609481 | 0.88 | PGR (0.39) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4752244 | 0.88 | PGR (0.39) | PGR | |
| SCHEMBL4748817 | 0.87 | PGR (0.34) | PGR | |
| SCHEMBL4607471 | 0.87 | PGR (0.43) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4748729 | 0.87 | KDM4E (0.32) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL4621738 | 0.86 | PGR (0.38) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4752246 | 0.85 | PGR (0.38) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4751300 | 0.85 | PGR (0.36) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4748816 | 0.84 | PGR (0.36) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |