Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607471 | 0.91 | PGR (0.43) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4621738 | 0.90 | PGR (0.38) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4748819 | 0.88 | PGR (0.37) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL21010535 | 0.88 | PGR (0.34) | PGR | |
| SCHEMBL4607965 | 0.87 | PGR (0.42) | PGRSLC22A12 | |
| SCHEMBL4752246 | 0.86 | PGR (0.38) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4751300 | 0.86 | PGR (0.36) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4608810 | 0.84 | PGR (0.34) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4904300 | 0.84 | PGR (0.34) | PGRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4748817 | 0.83 | PGR (0.34) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948615-B1 | Pyrazole derivatives useful for the treatment of gynaecological diseases | PFIZER LTD (GB) | 2011-12-14 | — | — | EP | claimed |
| US-7425569-B2 | 1H-pyrazoles useful in therapy | PFIZER INC (US) | 2008-09-16 | — | — | US | claimed |
| EP-1948615-A2 | COMPOUNDS USEFUL IN THERAPY | Pfizer Limited (GB) | 2008-07-30 | — | — | EP | claimed |
| US-20080085919-A1 | 1H-Pyrazoles Useful In Therapy | BRADLEY PAUL A | 2008-04-10 | — | — | US | claimed |
| US-7309712-B2 | 1H-pyrazoles useful in therapy | PFIZER LIMITED (GB) | 2007-12-18 | — | — | US | claimed |
| WO-2007054770-A2 | PYRAZOLE DERIVATIVES AND THEIR MEDICAL USE | PFIZER LIMITED (GB) | 2007-05-18 | — | — | WO | claimed |
| US-20070105909-A1 | Compounds useful in therapy | PFIZER INC. | 2007-05-10 | — | — | US | claimed |
| WO-2025068686-A1 | TREATMENT FOR BATTEN DISEASE | THE ROYAL VETERINARY COLLEGE (GB) | 2025-04-03 | — | — | WO | disclosed |
| US-20190145979-A9 | METHODS AND SYSTEMS FOR IDENTIFYING AND TREATING ANTI-PROGESTIN SENSITIVE TUMORS | INVIVIS PHARMACEUTICALS INC. (US) | 2019-05-16 | — | — | US | disclosed |
| US-20190145979-A9 | METHODS AND SYSTEMS FOR IDENTIFYING AND TREATING ANTI-PROGESTIN SENSITIVE TUMORS | INVIVIS PHARMACEUTICALS INC. (US) | 2019-05-16 | — | — | US | disclosed |
| EP-3129786-A1 | SYSTEMS AND METHODS FOR IDENTIFYING PROGESTERONE RECEPTOR SUBTYPES | Arno Therapeutics Inc. (US) | 2017-02-15 | — | — | EP | disclosed |
| WO-2015157343-A1 | SYSTEMS AND METHODS FOR IDENTIFYING PROGESTERONE RECEPTOR SUBTYPES | ARNO THERAPEUTICS, INC. (US) | 2015-10-15 | — | — | WO | disclosed |
| US-20150285803-A1 | SYSTEMS AND METHODS FOR IDENTIFYING PROGESTERONE RECEPTOR SUBTYPES | INVIVIS PHARMACEUTICALS INC. (US) | 2015-10-08 | — | — | US | disclosed |
| US-20130095170-A1 | METHODS AND SYSTEMS FOR IDENTIFYING AND TREATING ANTI-PROGESTIN SENSITIVE TUMORS | INVIVIS PHARMACEUTICALS INC. | 2013-04-18 | — | — | US | disclosed |
| WO-2013052652-A1 | METHODS AND SYSTEMS FOR IDENTIFYING AND TREATING ANTI-PROGESTIN SENSITIVE TUMORS | GILLES ERARD (US) | 2013-04-11 | — | — | WO | disclosed |
| EP-1948615-B1 | Pyrazole derivatives useful for the treatment of gynaecological diseases | PFIZER LTD (GB) | 2011-12-14 | — | — | EP | disclosed |
| EP-1948615-A2 | COMPOUNDS USEFUL IN THERAPY | Pfizer Limited (GB) | 2008-07-30 | — | — | EP | disclosed |
| US-7309712-B2 | 1H-pyrazoles useful in therapy | PFIZER LIMITED (GB) | 2007-12-18 | — | — | US | disclosed |
| WO-2007054770-A2 | PYRAZOLE DERIVATIVES AND THEIR MEDICAL USE | PFIZER LIMITED (GB) | 2007-05-18 | — | — | WO | disclosed |
| US-20070105909-A1 | Compounds useful in therapy | PFIZER INC. | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105909-A1 | Compounds useful in therapy | GNRHR, OPRK1, CBR3 | PGR 155/4885KDM4E 1423/4885MEN1 989/4885 |
| US-20080085919-A1 | 1H-Pyrazoles Useful In Therapy | CBR3, GNRHR, RXFP3 | PGR 87/4885KDM4E 2056/4885MEN1 1373/4885 |
| US-20190145979-A9 | METHODS AND SYSTEMS FOR IDENTIFYING AND TREATING ANTI-PROGESTIN SENSITIVE TUMORS | PGR, PGRMC2, PGRMC1 | PGR 1/4885KDM4E 4444/4885MEN1 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.