Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMPD2 | Q01433 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072995 | 0.83 | ALDH1A1 (0.41) | AMPD2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27979606 | 0.79 | GAA (0.45) | AMPD2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4748786 | 0.75 | CYP2D6 (0.44) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL11295999 | 0.75 | CYP2D6 (0.44) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL3733166 | 0.74 | TSHR (0.52) | AMPD2ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL25000116 | 0.73 | CYP2D6 (0.48) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL11064509 | 0.73 | CYP3A4 (0.47) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL11076847 | 0.73 | CYP3A4 (0.45) | AMPD2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14828739 | 0.72 | TSHR (0.51) | AMPD2ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL1920939 | 0.71 | GAA (0.59) | AMPD2ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135525-A2 | SUBSTITUTED AZETIDINES, MANUFACTURING AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |