Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975419 | 0.86 | CYP3A4 (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19OPRM1 | |
| SCHEMBL11064509 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19OPRM1 | |
| SCHEMBL11077002 | 0.81 | TP53 (0.44) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL11072966 | 0.81 | CYP3A4 (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19OPRM1 | |
| SCHEMBL10934389 | 0.76 | ALDH1A1 (0.49) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19974745 | 0.75 | LMNA (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19OPRM1 | |
| SCHEMBL19974843 | 0.73 | LMNA (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19OPRM1 | |
| SCHEMBL7699024 | 0.73 | CYP3A4 (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19OPRM1 | |
| SCHEMBL4748917 | 0.73 | AMPD2 (0.44) | CYP3A4LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8881736 | 0.73 | CASP3 (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432901-A | CHEMICAL INTERMEDIATE FOR PENICIULINS, THIENAMYCINS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-02-21 | — | — | US | disclosed |