Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3678097 | 1.00 | PKM (0.48) | PKMKMT2AMEN1LMNAMAPT | |
| SCHEMBL13409983 | 0.94 | PKM (0.54) | PKMKMT2AMEN1LMNAMAPT | |
| SCHEMBL4749013 | 0.87 | PKM (0.48) | PKMKMT2AMEN1LMNAMAPT | |
| SCHEMBL3678098 | 0.87 | PKM (0.48) | PKMKMT2AMEN1LMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL3690901 | 0.82 | S1PR2 (0.46) | ALDH1A1NPSR1L3MBTL1S1PR1S1PR3 | |
| SCHEMBL3689174 | 0.82 | PKM (0.53) | PKMKMT2AMEN1LMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL3691241 | 0.81 | S1PR2 (0.44) | LMNAALDH1A1HTTNPSR1SMN1; SMN2 | |
| Iodide SCHEMBL3682168 | 0.81 | PKM (0.47) | PKMKMT2AMEN1LMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL3691236 | 0.77 | NPSR1 (0.46) | ALDH1A1NPSR1L3MBTL1S1PR1S1PR3 | |
| SCHEMBL13409989 | 0.75 | S1PR2 (0.52) | ALDH1A1NPSR1L3MBTL1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |