Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.43 |
| ▸ | IRS1 | P35568 | 1/20 | 0.43 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3691241 | 0.99 | S1PR2 (0.44) | S1PR2S1PR1S1PR3S1PR4AKT1 | |
| Trifluoroacetic Acid SCHEMBL3691236 | 0.94 | NPSR1 (0.46) | S1PR2S1PR1S1PR3S1PR4AKT1 | |
| SCHEMBL13409989 | 0.93 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR4AKT1 | |
| SCHEMBL13409941 | 0.92 | S1PR2 (0.50) | S1PR2S1PR1S1PR3S1PR4AKT1 | |
| Trifluoroacetic Acid SCHEMBL3682804 | 0.86 | MMP2 (0.40) | S1PR2S1PR1S1PR3S1PR4AKT1 | |
| Trifluoroacetic Acid SCHEMBL3682809 | 0.86 | MMP2 (0.40) | S1PR2S1PR1S1PR3S1PR4AKT1 | |
| SCHEMBL3690902 | 0.84 | FAAH (0.41) | S1PR1S1PR3S1PR4AKT1IRS1 | |
| Trifluoroacetic Acid SCHEMBL3679726 | 0.84 | MMP9 (0.57) | — | |
| Trifluoroacetic Acid SCHEMBL3679731 | 0.84 | MMP9 (0.57) | — | |
| SCHEMBL3691243 | 0.83 | FAAH (0.40) | S1PR1S1PR3S1PR4AKT1IRS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | S1PR2 413/4885S1PR1 400/4885S1PR3 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.