Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749085 | 1.00 | HTR1A (0.31) | HTR1ADRD2DRD1DRD4DRD5 | |
| SCHEMBL4749288 | 0.91 | KDM2B (0.31) | KDM2B | |
| SCHEMBL4749084 | 0.91 | KDM2B (0.31) | KDM2B | |
| SCHEMBL4749303 | 0.91 | KDM2B (0.31) | KDM2B | |
| SCHEMBL4749092 | 0.91 | KDM2B (0.31) | KDM2B | |
| SCHEMBL4751707 | 0.89 | TACR1 (0.30) | — | |
| SCHEMBL4752773 | 0.89 | TACR1 (0.30) | — | |
| SCHEMBL4751702 | 0.89 | TACR1 (0.30) | — | |
| SCHEMBL4752774 | 0.89 | TACR1 (0.30) | — | |
| SCHEMBL4751978 | 0.87 | KDM2B (0.30) | KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |