Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 9/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.52 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204139 | 0.85 | HPGD (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15246662 | 0.84 | HDAC3 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2884335 | 0.83 | PTGS2 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15914501 | 0.82 | TRAP1 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14714191 | 0.82 | HDAC3 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10045885 | 0.81 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15914502 | 0.81 | TRAP1 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3453990 | 0.78 | HSD17B10 (0.61) | HDAC6SLC6A2SLC6A3MEN1ADORA3 | |
| SCHEMBL10045853 | 0.77 | HDAC3 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5925218 | 0.76 | HDAC6 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122356-A1 | CARDIOVASCULAR AGENTS | CTG PHARMA S.R.L. (IT) | 2008-10-16 | — | — | WO | claimed |