Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749377 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL13665941 | 0.87 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL4748813 | 0.86 | KMT2A (0.60) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL14041425 | 0.86 | KMT2A (0.60) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL4746375 | 0.74 | KMT2A (0.62) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL4746370 | 0.74 | KMT2A (0.62) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL15964178 | 0.73 | MEN1 (0.52) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL15686555 | 0.73 | CD274 (0.41) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL14198801 | 0.73 | KMT2A (0.67) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL12924705 | 0.73 | KMT2A (0.67) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | disclosed |