Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 9/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749545 | 0.92 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL4808665 | 0.88 | CHRM4 (0.85) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL4808676 | 0.88 | CHRM4 (0.85) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL4813747 | 0.87 | CHRM4 (0.83) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL4813731 | 0.87 | CHRM4 (0.83) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL4749749 | 0.85 | CHRM1 (0.47) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL4648728 | 0.83 | CHRM1 (0.66) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL4811240 | 0.82 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL4811227 | 0.82 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL14042818 | 0.82 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |