Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 9/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749527 | 0.88 | MC4R (0.38) | KDM2BMC4RGSK3BNTRK1RXFP1 | |
| SCHEMBL4021139 | 0.87 | KDM2B (0.43) | KDM2BMC4RKMT2AKDM4EMEN1 | |
| SCHEMBL4026436 | 0.86 | KDM2B (0.42) | KDM2BMC4RRXFP1ALDH1A1KMT2A | |
| SCHEMBL4020026 | 0.85 | KDM2B (0.42) | KDM2BMC4RALDH1A1KMT2AKDM4E | |
| SCHEMBL4026512 | 0.84 | NPC1 (0.41) | KDM2BMC4RNTRK1KMT2AMEN1 | |
| SCHEMBL4780053 | 0.84 | MC4R (0.44) | MC4RNTRK1ALDH1A1KMT2AGAA | |
| SCHEMBL4749342 | 0.83 | KDM2B (0.40) | KDM2BMC4RALDH1A1KMT2ALMNA | |
| SCHEMBL4024597 | 0.82 | KDM2B (0.45) | KDM2BALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4021398 | 0.82 | KDM2B (0.45) | KDM2BALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4751807 | 0.81 | MC4R (0.42) | MC4RNTRK1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |