Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749407 | 0.88 | EED (0.32) | L3MBTL1KMT2ASMN1; SMN2EEDGAA | |
| SCHEMBL4749061 | 0.86 | EED (0.37) | HPGDL3MBTL1KMT2ACCKBRCACNA1G | |
| SCHEMBL4749058 | 0.86 | EED (0.37) | HPGDL3MBTL1KMT2ACCKBRCACNA1G | |
| SCHEMBL4749099 | 0.82 | POLB (0.38) | HPGDL3MBTL1KMT2ACCKBRCACNA1G | |
| SCHEMBL4749101 | 0.82 | POLB (0.38) | HPGDL3MBTL1KMT2ACCKBRCACNA1G | |
| SCHEMBL4749102 | 0.79 | POLB (0.36) | HPGDL3MBTL1KMT2ACCKBRCACNA1G | |
| SCHEMBL4749201 | 0.78 | MEN1 (0.44) | KMT2ACCKBRCACNA1GCACNA1HCACNA1I | |
| SCHEMBL4019577 | 0.76 | EED (0.37) | L3MBTL1KMT2ACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL4019982 | 0.75 | KMT2A (0.39) | KMT2AEEDALDH1A1LMNA | |
| SCHEMBL4019987 | 0.75 | KMT2A (0.39) | KMT2AEEDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |