Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FABP6 | P51161 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749201 | 0.89 | MEN1 (0.44) | POLBKMT2ACCKBRCACNA1GCACNA1H | |
| SCHEMBL4748993 | 0.89 | MEN1 (0.44) | POLBKMT2ACCKBRCACNA1GCACNA1H | |
| SCHEMBL4749099 | 0.87 | POLB (0.38) | POLBHPGDL3MBTL1KMT2ACCKBR | |
| SCHEMBL4749101 | 0.87 | POLB (0.38) | POLBHPGDL3MBTL1KMT2ACCKBR | |
| SCHEMBL4749058 | 0.86 | EED (0.37) | POLBHPGDL3MBTL1KMT2ACCKBR | |
| SCHEMBL4749061 | 0.86 | EED (0.37) | POLBHPGDL3MBTL1KMT2ACCKBR | |
| SCHEMBL4749432 | 0.84 | CYP2D6 (0.34) | KMT2AMEN1MC4R | |
| SCHEMBL4020633 | 0.84 | MEN1 (0.35) | KMT2AMEN1MC4R | |
| SCHEMBL4027216 | 0.83 | KMT2A (0.41) | KMT2AMEN1GAAMC4RALDH1A1 | |
| SCHEMBL4026485 | 0.82 | ALDH1A1 (0.48) | L3MBTL1KMT2AMEN1GAASLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |