SCHEMBL4749447 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	BCHE	P06276	1/20	0.36

▸	MGLL	Q99685	8/20	0.35

▸	OPRK1	P41145	6/20	0.35

▸	OPRD1	P41143	5/20	0.35

▸	MAPT	P10636	2/20	0.34

▸	NPSR1	Q6W5P4	1/20	0.34

▸	RAB9A	P51151	2/20	0.34

▸	OPRM1	P35372	4/20	0.33

▸	L3MBTL1	Q9Y468	1/20	0.33

▸	PROKR1	Q8TCW9	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4749494	1.00	BCHE (0.36)	BCHEMGLLOPRK1OPRD1MAPT
SCHEMBL4749427	1.00	BCHE (0.36)	BCHEMGLLOPRK1OPRD1MAPT
SCHEMBL4751374	0.89	BCHE (0.32)	BCHEOPRK1OPRD1
SCHEMBL4752894	0.81	MGLL (0.34)	MGLLOPRK1OPRD1
SCHEMBL4021758	0.81	MGLL (0.36)	BCHEMGLLOPRK1OPRD1OPRM1
SCHEMBL4021764	0.81	MGLL (0.36)	BCHEMGLLOPRK1OPRD1OPRM1
SCHEMBL4752896	0.81	MGLL (0.34)	MGLLOPRK1OPRD1
SCHEMBL4787104	0.79	HRH4 (0.37)	MGLL
SCHEMBL4752082	0.79	HRH4 (0.37)	MGLL
SCHEMBL4752185	0.79	RAB9A (0.37)	BCHEMGLLRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008140810-A1	CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS	CYTOKINETICS, INCORPORATED (US)	2008-11-20	—	—	WO	disclosed