Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749507 | 0.90 | MC4R (0.31) | KDR | |
| SCHEMBL4749122 | 0.89 | KDR (0.35) | KDR | |
| SCHEMBL4749384 | 0.87 | MC4R (0.30) | — | |
| SCHEMBL4751996 | 0.82 | KIF11 (0.31) | KDR | |
| SCHEMBL4751647 | 0.82 | KIF11 (0.31) | KDR | |
| SCHEMBL4751959 | 0.82 | KIF11 (0.33) | KDR | |
| SCHEMBL4751648 | 0.82 | KIF11 (0.31) | KDR | |
| SCHEMBL4751340 | 0.82 | KIF11 (0.31) | — | |
| SCHEMBL4749253 | 0.82 | KIF11 (0.32) | — | |
| SCHEMBL4749257 | 0.82 | KIF11 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |