Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.30 |
| ▸ | EED | O75530 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751996 | 0.95 | KIF11 (0.31) | KIF11HTR7BCHEKDR | |
| SCHEMBL4749253 | 0.95 | KIF11 (0.32) | KIF11 | |
| SCHEMBL4751340 | 0.95 | KIF11 (0.31) | KIF11 | |
| SCHEMBL4749257 | 0.95 | KIF11 (0.32) | KIF11 | |
| SCHEMBL4751647 | 0.94 | KIF11 (0.31) | KIF11HTR7BCHEKDR | |
| SCHEMBL4751648 | 0.94 | KIF11 (0.31) | KIF11HTR7BCHEKDR | |
| SCHEMBL4749375 | 0.92 | MEN1 (0.31) | — | |
| SCHEMBL4749372 | 0.92 | MEN1 (0.31) | — | |
| SCHEMBL4025347 | 0.90 | KIF11 (0.37) | KIF11HTR7BCHEKDR | |
| SCHEMBL4748982 | 0.89 | KIF11 (0.32) | KIF11HTR7BCHEKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |