Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3083716 | 0.83 | KMT2A (0.53) | KMT2AMEN1HPGDHSD17B10APAF1 | |
| SCHEMBL4303680 | 0.76 | HSD17B10 (0.47) | HSD17B10APAF1HTTPOLB | |
| SCHEMBL9674221 | 0.75 | KMT2A (0.60) | KMT2AMEN1HPGDHSD17B10APAF1 | |
| SCHEMBL18783299 | 0.73 | FGFR1 (0.57) | HPGDHTTFGFR1 | |
| SCHEMBL1147353 | 0.72 | USP5 (0.66) | KMT2AMEN1HPGDHSD17B10APAF1 | |
| SCHEMBL18258627 | 0.72 | USP5 (0.66) | KMT2AMEN1HPGDHSD17B10APAF1 | |
| SCHEMBL30874960 | 0.72 | USP5 (0.66) | KMT2AMEN1HPGDHSD17B10APAF1 | |
| SCHEMBL22234465 | 0.71 | HSD17B10 (0.53) | KMT2AMEN1HPGDHSD17B10APAF1 | |
| SCHEMBL4292120 | 0.71 | OPRD1 (0.43) | KMT2AMEN1POLBLMNATSHR | |
| SCHEMBL14638103 | 0.71 | MEN1 (0.64) | KMT2AMEN1HPGDHSD17B10APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |