Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FKBP5 | Q13451 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292712 | 1.00 | DRD3 (0.46) | DRD3KMT2AFKBP1ATP53ALDH1A1 | |
| SCHEMBL4752088 | 0.92 | DRD3 (0.38) | DRD3KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL4282314 | 0.92 | DRD3 (0.38) | DRD3KMT2AALDH1A1L3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL4287144 | 0.86 | HPGD (0.47) | DRD3KMT2ATP53ALDH1A1HPGD | |
| SCHEMBL8125847 | 0.85 | PDE4B (0.49) | DRD3TP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4295442 | 0.85 | KDM4E (0.47) | KMT2AALDH1A1L3MBTL1HPGDMEN1 | |
| SCHEMBL4281738 | 0.85 | REN (0.37) | KMT2AALDH1A1L3MBTL1HPGDTSHR | |
| SCHEMBL4292801 | 0.85 | KDM4E (0.40) | KMT2ATP53ALDH1A1HPGDTSHR | |
| SCHEMBL4752327 | 0.85 | REN (0.37) | KMT2AALDH1A1L3MBTL1HPGDTSHR | |
| SCHEMBL4281811 | 0.85 | PTGES (0.42) | KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |