Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.77 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752579 | 1.00 | P2RY12 (0.77) | P2RY12USP28ADORA3ADORA2BADORA1 | |
| SCHEMBL4752571 | 0.86 | P2RY12 (0.59) | P2RY12ADORA3ADORA2BADORA1 | |
| SCHEMBL7477673 | 0.85 | P2RY12 (0.58) | P2RY12ADORA3 | |
| SCHEMBL4750106 | 0.83 | P2RY12 (0.55) | P2RY12ADORA3 | |
| SCHEMBL4750111 | 0.82 | P2RY12 (0.77) | P2RY12 | |
| SCHEMBL4752949 | 0.78 | P2RY12 (0.71) | P2RY12 | |
| Bicarbonate SCHEMBL7510959 | 0.76 | P2RY12 (0.73) | P2RY12USP28 | |
| SCHEMBL6995281 | 0.75 | P2RY12 (1.00) | P2RY12ADORA3 | |
| SCHEMBL6995290 | 0.75 | P2RY12 (1.00) | P2RY12ADORA3 | |
| SCHEMBL4752109 | 0.75 | P2RY12 (0.54) | P2RY12USP28ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4084415-B2 | — | — | 2008-04-30 | — | — | JP | claimed |
| EP-0840740-B1 | NEW INHIBITORS OF PLATELET AGGREGATION | ASTRAZENECA AB (SE) | 2002-05-02 | — | — | EP | claimed |