Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 2/20 | 0.31 |
| ▸ | PDE8B | O95263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750414 | 0.86 | P2RY12 (0.77) | P2RY12ADORA3ADORA2BADORA1 | |
| SCHEMBL4752579 | 0.86 | P2RY12 (0.77) | P2RY12ADORA3ADORA2BADORA1 | |
| SCHEMBL7477673 | 0.77 | P2RY12 (0.58) | P2RY12ADORA3 | |
| SCHEMBL4750106 | 0.71 | P2RY12 (0.55) | P2RY12ADORA3 | |
| SCHEMBL4750111 | 0.68 | P2RY12 (0.77) | P2RY12 | |
| SCHEMBL4752949 | 0.67 | P2RY12 (0.71) | P2RY12 | |
| SCHEMBL4752109 | 0.63 | P2RY12 (0.54) | P2RY12ADORA3 | |
| SCHEMBL7472744 | 0.61 | P2RY12 (0.64) | P2RY12ADORA3 | |
| Bicarbonate SCHEMBL7510959 | 0.61 | P2RY12 (0.73) | P2RY12 | |
| SCHEMBL6995281 | 0.60 | P2RY12 (1.00) | P2RY12ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4084415-B2 | — | — | 2008-04-30 | — | — | JP | claimed |
| EP-0840740-B1 | NEW INHIBITORS OF PLATELET AGGREGATION | ASTRAZENECA AB (SE) | 2002-05-02 | — | — | EP | claimed |