Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 10/20 | 0.39 |
| ▸ | CCKAR | P32238 | 8/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749832 | 0.90 | MEN1 (0.47) | CCR2CCKBRCCKARTDP1 | |
| SCHEMBL4749826 | 0.88 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL4749806 | 0.84 | CCKBR (0.50) | CCKBRCCKARTDP1 | |
| SCHEMBL1886229 | 0.82 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL1886233 | 0.82 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL4749848 | 0.82 | CCKBR (0.48) | CCR2KCNA5CCKBRCCKARPTGER4 | |
| SCHEMBL4747556 | 0.82 | CCKBR (0.48) | CCR2KCNA5CCKBRCCKARPTGER4 | |
| SCHEMBL3900180 | 0.82 | CCKBR (0.63) | CCKBRCCKAR | |
| SCHEMBL13792674 | 0.82 | CCKBR (0.63) | CCKBRCCKAR | |
| SCHEMBL3741167 | 0.78 | CCKAR (0.50) | CCR2CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124524-A2 | ARYL SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | claimed |