Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.48 |
| ▸ | CCKAR | P32238 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749848 | 1.00 | CCKBR (0.48) | CCKBRCCKARL3MBTL1SMN1; SMN2PTGER4 | |
| SCHEMBL4749806 | 0.86 | CCKBR (0.50) | CCKBRCCKAR | |
| SCHEMBL4749832 | 0.84 | MEN1 (0.47) | CCKBRCCKARPOLBCCR2 | |
| SCHEMBL4750489 | 0.82 | CCR2 (0.43) | CCKBRCCKARPTGER4PTGER2KCNA5 | |
| SCHEMBL3744724 | 0.81 | CCKBR (0.55) | CCKBRCCKARSMN1; SMN2ALDH1A1 | |
| SCHEMBL4749826 | 0.78 | CCKBR (0.52) | CCKBRCCKARL3MBTL1POLB | |
| SCHEMBL3752702 | 0.78 | CCKAR (0.56) | CCKBRCCKARPOLB | |
| SCHEMBL3901303 | 0.78 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL4747134 | 0.78 | CCR2 (0.57) | CCKBRCCKARPTGER4PTGER2KCNA5 | |
| SCHEMBL3751356 | 0.76 | CCKBR (0.54) | CCKBRCCKARHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124524-A2 | ARYL SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | claimed |
| WO-2008124524-A2 | ARYL SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | disclosed |