Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750795 | 0.89 | FFAR4 (0.36) | FFAR4HTR2ANPC1ALDH1A1HTR1A | |
| SCHEMBL4750498 | 0.88 | FFAR4 (0.36) | FFAR4HTR2ANPC1ALDH1A1HTR1A | |
| SCHEMBL4750793 | 0.87 | NPC1 (0.36) | FFAR4HTR2ANPC1ALDH1A1HTR1A | |
| SCHEMBL4752959 | 0.84 | HTR2A (0.47) | FFAR4HTR2ANPC1ALDH1A1HTR1A | |
| SCHEMBL5781658 | 0.84 | KMT2A (0.36) | HTR2ANPC1ALDH1A1KMT2ALMNA | |
| SCHEMBL2328393 | 0.79 | KMT2A (0.39) | HTR2ANPC1ALDH1A1KMT2ALMNA | |
| SCHEMBL4751070 | 0.79 | ALDH1A1 (0.41) | FFAR4NPC1ALDH1A1KMT2ALMNA | |
| SCHEMBL4750821 | 0.78 | ALDH1A1 (0.39) | HTR2ANPC1ALDH1A1KMT2ALMNA | |
| SCHEMBL4750506 | 0.78 | AKT1 (0.36) | FFAR4HTR2ANPC1ALDH1A1KMT2A | |
| SCHEMBL7963661 | 0.77 | NPC1 (0.55) | NPC1ALDH1A1HTR1AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |