Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18649397 | 0.85 | HTR2A (0.49) | HTR2AFFAR4ALDH1A1LMNA | |
| SCHEMBL4750508 | 0.84 | FFAR4 (0.36) | HTR2AFFAR4NPC1HTR1AALDH1A1 | |
| SCHEMBL17523384 | 0.82 | HTR2A (0.49) | HTR2AFFAR4ALDH1A1LMNA | |
| SCHEMBL4751070 | 0.80 | ALDH1A1 (0.41) | FFAR4NPC1ALDH1A1LMNA | |
| SCHEMBL4753146 | 0.80 | HTR2A (0.47) | HTR2AFFAR4NPC1ALDH1A1 | |
| SCHEMBL4750506 | 0.79 | AKT1 (0.36) | HTR2AFFAR4NPC1ALDH1A1LMNA | |
| SCHEMBL7963661 | 0.78 | NPC1 (0.55) | NPC1HTR1AALDH1A1LMNA | |
| SCHEMBL4752450 | 0.77 | LMNA (0.36) | FFAR4NPC1ALDH1A1LMNA | |
| SCHEMBL16111361 | 0.77 | FFAR4 (0.47) | HTR2AFFAR4ALDH1A1 | |
| SCHEMBL23667766 | 0.75 | NPC1 (0.44) | HTR2AFFAR4NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |