Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 6/20 | 0.53 |
| ▸ | GUSB | P08236 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611811 | 0.94 | DHFR (0.61) | DHFRGUSBKDM4EALDH1A1MEN1 | |
| SCHEMBL5611545 | 0.88 | GUSB (0.42) | DHFRGUSBKDM4EALDH1A1MEN1 | |
| SCHEMBL5611783 | 0.87 | CYP1A2 (0.43) | DHFRGUSBTSHRLMNAPIM1 | |
| SCHEMBL5612557 | 0.87 | DHFR (0.41) | DHFRGUSBMEN1KMT2AHPGD | |
| SCHEMBL5611922 | 0.87 | DHFR (0.58) | DHFRGUSBKDM4EALDH1A1MEN1 | |
| SCHEMBL5611690 | 0.86 | HPGD (0.43) | DHFRGUSBKDM4EALDH1A1MEN1 | |
| SCHEMBL5611856 | 0.86 | GUSB (0.45) | DHFRGUSBMEN1KMT2AHPGD | |
| SCHEMBL5611667 | 0.85 | DHFR (0.56) | DHFRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5612460 | 0.83 | GUSB (0.43) | DHFRGUSBKDM4EALDH1A1MEN1 | |
| SCHEMBL5611734 | 0.83 | DHFR (0.55) | DHFRGUSBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | disclosed |