Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750784 | 0.88 | DHFR (0.53) | GUSBDHFRHPGDKMT2AMEN1 | |
| SCHEMBL5612482 | 0.86 | GUSB (0.41) | GUSBDHFRHPGDKMT2AMEN1 | |
| SCHEMBL5611856 | 0.84 | GUSB (0.45) | GUSBDHFRHPGDKMT2AMEN1 | |
| SCHEMBL5611766 | 0.84 | GUSB (0.42) | GUSBHPGDKMT2AMEN1LMNA | |
| SCHEMBL5612557 | 0.83 | DHFR (0.41) | GUSBDHFRHPGDKMT2AMEN1 | |
| SCHEMBL5611811 | 0.82 | DHFR (0.61) | GUSBDHFRHPGDKMT2AMEN1 | |
| SCHEMBL5611783 | 0.82 | CYP1A2 (0.43) | GUSBDHFRLMNAPIM1CSNK2A2 | |
| SCHEMBL5611690 | 0.81 | HPGD (0.43) | GUSBDHFRHPGDKMT2AMEN1 | |
| SCHEMBL5612460 | 0.80 | GUSB (0.43) | GUSBDHFRHPGDKMT2AMEN1 | |
| SCHEMBL5611669 | 0.80 | DHFR (0.51) | GUSBDHFRHPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | disclosed |