Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033959 | 0.86 | MAPT (0.66) | CTSBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4748494 | 0.86 | CTSB (0.55) | CTSBKMT2AMEN1PKMMAPT | |
| SCHEMBL18343631 | 0.86 | CTSB (0.55) | CTSBKMT2AMEN1PKMMAPT | |
| SCHEMBL14247753 | 0.86 | CTSB (0.61) | CTSBKMT2AMEN1PKMMAPT | |
| SCHEMBL7322890 | 0.85 | CTSB (0.66) | CTSBKMT2AMEN1PKMMAPT | |
| SCHEMBL17327480 | 0.84 | MEN1 (0.49) | CTSBKMT2AMEN1PKMMAPT | |
| SCHEMBL9538655 | 0.83 | CTSB (0.58) | CTSBKMT2AMEN1PKMMAPT | |
| SCHEMBL3708321 | 0.79 | MAOA (0.63) | CTSBKMT2AMEN1MAPTLMNA | |
| SCHEMBL9395569 | 0.79 | MAPT (0.72) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL18547825 | 0.78 | CTSB (0.61) | CTSBKMT2APKMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134354-A1 | TNF-α PRODUCTION INHIBITOR | ARRAY BIOPHARMA, INC. (US) | 2008-11-06 | — | — | WO | disclosed |