Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13151306 | 0.86 | TOP2A (0.47) | TOP2ANPBWR1ALDH1A1KDM4EMAPT | |
| SCHEMBL1031479 | 0.85 | TOP2A (0.49) | TOP2ANPBWR1ALDH1A1KDM4EMAPT | |
| SCHEMBL19631128 | 0.82 | TAAR1 (0.51) | TOP2ANPBWR1ALDH1A1KDM4EMAPT | |
| SCHEMBL31284789 | 0.81 | TOP2A (0.48) | TOP2ANPBWR1ALDH1A1KDM4EMAPT | |
| SCHEMBL30946374 | 0.80 | TOP2A (0.52) | TOP2ANPBWR1ALDH1A1KDM4EMAPT | |
| SCHEMBL18377688 | 0.80 | ALDH1A1 (0.54) | TOP2ANPBWR1ALDH1A1KDM4EMAPT | |
| SCHEMBL31285046 | 0.78 | TOP2A (0.48) | TOP2ANPBWR1ALDH1A1KDM4EMAPT | |
| SCHEMBL13151274 | 0.77 | NPBWR1 (0.46) | TOP2ANPBWR1ALDH1A1KDM4EMAPT | |
| SCHEMBL18367564 | 0.76 | TOP2A (0.49) | TOP2ANPBWR1ALDH1A1KDM4EMAPT | |
| SCHEMBL27840090 | 0.75 | TOP2A (0.48) | TOP2ANPBWR1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904489-A2 | PROCESS FOR THE SYNTHESIS OF TRIAZOLES | Rib-X Pharmaceuticals, Inc. (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006133397-A2 | PROCESS FOR THE SYNTHESIS OF TRIAZOLES | RIB-X PHARMACEUTICALS, INC. (US) | 2006-12-14 | — | — | WO | disclosed |