Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750451 | 0.93 | CCKBR (0.52) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4749827 | 0.90 | CCKBR (0.45) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4750072 | 0.87 | KCNA5 (0.55) | MEN1KMT2AHPGDCCKBRCCR2 | |
| SCHEMBL3740981 | 0.82 | CCKAR (0.53) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13011860 | 0.82 | CCKAR (0.53) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3741167 | 0.82 | CCKAR (0.50) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3745887 | 0.79 | GRIK1 (0.56) | CCKBRCCR2 | |
| SCHEMBL3752702 | 0.78 | CCKAR (0.56) | LMNAMEN1KMT2AMAPTCCKBR | |
| SCHEMBL1887006 | 0.77 | CCKBR (0.59) | CCKBRCCKAR | |
| SCHEMBL4749807 | 0.77 | CCKBR (0.54) | MEN1KMT2AALDH1A1CCKBRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124524-A2 | ARYL SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | claimed |