Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.55 |
| ▸ | CCKBR | P32239 | 5/20 | 0.55 |
| ▸ | CCKAR | P32238 | 5/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751037 | 0.87 | LMNA (0.49) | KCNA5CCKBRCCKARHPGDCCR2 | |
| SCHEMBL4749827 | 0.85 | CCKBR (0.45) | KCNA5CCKBRCCKARHPGDCCR2 | |
| SCHEMBL3752702 | 0.83 | CCKAR (0.56) | CCKBRCCKARMEN1KMT2A | |
| SCHEMBL3745887 | 0.81 | GRIK1 (0.56) | CCKBRCCR2 | |
| SCHEMBL4750451 | 0.81 | CCKBR (0.52) | KCNA5CCKBRCCKARHPGDMEN1 | |
| SCHEMBL3741167 | 0.79 | CCKAR (0.50) | CCKBRCCKARHPGDCCR2MEN1 | |
| SCHEMBL3739784 | 0.76 | CCKAR (0.66) | CCKBRCCKAR | |
| SCHEMBL3739788 | 0.76 | CCKAR (0.66) | CCKBRCCKAR | |
| SCHEMBL3755955 | 0.76 | CCKAR (0.56) | KCNA5CCKBRCCKAR | |
| SCHEMBL3745925 | 0.76 | CCKAR (0.66) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124524-A2 | ARYL SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | claimed |