Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751405 | 0.97 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL4751100 | 0.88 | TSHR (0.45) | TSHRTHRB | |
| SCHEMBL4753687 | 0.88 | TSHR (0.45) | TSHRTHRB | |
| SCHEMBL615161 | 0.87 | TSHR (0.56) | TSHRTHRBALDH1A1 | |
| SCHEMBL615473 | 0.78 | TSHR (0.53) | TSHRTHRBALDH1A1 | |
| SCHEMBL4595250 | 0.77 | TSHR (0.43) | TSHRTHRBALDH1A1 | |
| SCHEMBL16534864 | 0.76 | TSHR (0.55) | TSHRTHRBALDH1A1 | |
| SCHEMBL977527 | 0.76 | TSHR (0.55) | TSHRTHRBALDH1A1 | |
| SCHEMBL2772530 | 0.76 | TSHR (0.55) | TSHRTHRBALDH1A1 | |
| SCHEMBL4753649 | 0.75 | TSHR (0.46) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149375-A1 | IMPROVED ORGANOSILICON COMPOUNDS | RANKA, SEEMA, AJAY (IN) | 2008-12-11 | — | — | WO | claimed |
| US-20080009644-A1 | Organosilicon Compounds | ZYDEX INDUSTRIES | 2008-01-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009644-A1 | Organosilicon Compounds | CUL1, CUL3, MGAM | TSHR 4731/4885THRB 4707/4885ALDH1A1 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.