Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD5 | P21918 | 2/20 | 0.40 |
| ▸ | HHAT | Q5VTY9 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LHCGR | P22888 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3304815 | 1.00 | DRD2 (0.40) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL4751909 | 0.83 | NPC1 (0.49) | NPC1RAB9A | |
| SCHEMBL4751918 | 0.78 | DRD2 (0.42) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL3302736 | 0.78 | HHAT (0.44) | DRD1HHATKMT2APOLBMAPK1 | |
| SCHEMBL7584752 | 0.77 | DRD3 (0.40) | DRD2DRD3HHATKMT2A | |
| SCHEMBL2836823 | 0.77 | DRD1 (0.41) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2872457 | 0.77 | HHAT (0.40) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL4752619 | 0.76 | DRD2 (0.43) | DRD2DRD3DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL2836479 | 0.76 | DDB1 (0.41) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2836992 | 0.76 | KDM4E (0.38) | HHATLHCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |