Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702771 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL4751315 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL4750946 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL8641626 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL8640654 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL9805946 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL4270369 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL8645590 | 1.00 | — | — | |
| SCHEMBL2228165 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL6714607 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996316-A | Catalytic reacting a primart amine with formaldehyde and hydrogen | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | claimed |
| WO-2008125557-A1 | USE OF ACYL UREAS IN DETERGENTS AND CLEANING AGENTS | HENKEL AG & CO. KGAA (DE) | 2008-10-23 | — | — | WO | disclosed |
| US-4996316-A | Catalytic reacting a primart amine with formaldehyde and hydrogen | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| EP-0037167-A1 | Manufacture of hydroperoxides | THE STANDARD OIL COMPANY (US) | 1981-10-07 | — | — | EP | disclosed |