Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.53 |
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29935870 | 0.87 | MAOA (0.58) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL2539617 | 0.87 | MAOA (0.58) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL5001878 | 0.83 | NPC1 (0.54) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL2533902 | 0.82 | MAOA (0.57) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL31139224 | 0.82 | MAOA (0.57) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL10032066 | 0.82 | ALDH1A1 (0.49) | RAB9AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8111540 | 0.81 | MAOA (0.55) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL30833931 | 0.81 | MAOA (0.55) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL5315248 | 0.80 | MAOA (0.62) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL5543437 | 0.79 | MAOA (0.66) | MAOAMAOBNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141239-A1 | IMIDAZOL [1,2-A] PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2008-11-20 | — | — | WO | disclosed |