Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097445 | 1.00 | BIRC2 (0.33) | BIRC2POLBNPSR1TDP1 | |
| SCHEMBL4817322 | 0.81 | BIRC2 (0.39) | BIRC2 | |
| SCHEMBL8097451 | 0.81 | BIRC2 (0.39) | BIRC2 | |
| SCHEMBL8105219 | 0.80 | — | — | |
| SCHEMBL8107189 | 0.77 | ABCB1 (0.33) | — | |
| SCHEMBL4751607 | 0.77 | ABCB1 (0.33) | — | |
| SCHEMBL4753924 | 0.73 | MME (0.30) | — | |
| SCHEMBL8097443 | 0.73 | MME (0.30) | — | |
| SCHEMBL4753975 | 0.72 | CTSS (0.32) | — | |
| SCHEMBL22089530 | 0.70 | MGAM (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151306-A1 | SYNTHESIS OF CYCLODEPSIPEPTIDE COMPOUNDS HAVING ANTINEOPLASTIC AND/OR ANTIMICROBIAL ACTIVITY | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |