Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 3/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097451 | 1.00 | BIRC2 (0.39) | BIRC2MMEMMP3MMP2MMP9 | |
| SCHEMBL8112737 | 0.82 | BIRC2 (0.34) | BIRC2 | |
| SCHEMBL8097445 | 0.81 | BIRC2 (0.33) | BIRC2 | |
| SCHEMBL4751635 | 0.81 | BIRC2 (0.33) | BIRC2 | |
| SCHEMBL8107196 | 0.75 | CTSK (0.47) | — | |
| SCHEMBL8108089 | 0.73 | BIRC2 (0.32) | BIRC2 | |
| SCHEMBL4753412 | 0.71 | ABCB1 (0.43) | — | |
| SCHEMBL8108824 | 0.71 | ABCB1 (0.43) | — | |
| SCHEMBL24822552 | 0.65 | BIRC2 (0.56) | BIRC2MME | |
| SCHEMBL8097553 | 0.64 | CTSK (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151306-A1 | SYNTHESIS OF CYCLODEPSIPEPTIDE COMPOUNDS HAVING ANTINEOPLASTIC AND/OR ANTIMICROBIAL ACTIVITY | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |