Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 13/20 | 0.67 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889158 | 0.83 | ERN1 (0.71) | ERN1TRIM24TRIM33TYRCDK1 | |
| SCHEMBL29559365 | 0.80 | ERN1 (1.00) | ERN1TRIM24TRIM33TYR | |
| SCHEMBL17618925 | 0.80 | ERN1 (0.67) | ERN1TRIM24TRIM33TYRCDK1 | |
| SCHEMBL120412 | 0.80 | ERN1 (1.00) | ERN1TRIM24TRIM33TYR | |
| SCHEMBL14697028 | 0.79 | ERN1 (0.60) | ERN1TRIM24TRIM33TYRCDK1 | |
| SCHEMBL31587586 | 0.79 | ERN1 (0.60) | ERN1TRIM24TRIM33TYRCDK1 | |
| SCHEMBL29673489 | 0.78 | ERN1 (0.96) | ERN1TRIM24TRIM33TYR | |
| SCHEMBL1509547 | 0.78 | ERN1 (0.65) | ERN1TRIM24TRIM33TYRCDK1 | |
| SCHEMBL20339337 | 0.78 | ERN1 (0.96) | ERN1TRIM24TRIM33TYR | |
| SCHEMBL3887594 | 0.77 | ERN1 (0.62) | ERN1TRIM24TRIM33TYRCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144483-A2 | AGENTS FOR TREATING DISORDERS INVOLVING MODULATION OF RYANODINE RECEPTORS | ARMGO PHARMA, INC. (US) | 2008-11-27 | — | — | WO | disclosed |