SCHEMBL3889158

SCHEMBL3889158

O=Cc1cc(Oc2ccc(O)c(C=O)c2)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 14/20 0.71
TRIM24 O15164 2/20 0.50
TRIM33 Q9UPN9 2/20 0.50
TYR P14679 1/20 0.50
CDK1 P06493 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3887594 0.92 ERN1 (0.62) ERN1TRIM24TRIM33TYRCDK1
SCHEMBL6093640 0.91 ERN1 (0.61) ERN1TRIM24TRIM33TYRCDK1
SCHEMBL9048075 0.89 ERN1 (0.59) ERN1TRIM24TRIM33TYRCDK1
SCHEMBL31287760 0.88 ERN1 (0.57) ERN1TRIM24TRIM33TYRCDK1
SCHEMBL9729990 0.85 ERN1 (0.58) ERN1TRIM24TRIM33TYR
SCHEMBL12952823 0.85 ERN1 (0.54) ERN1TRIM24TRIM33TYRCDK1
SCHEMBL16232845 0.83 ERN1 (0.53) ERN1TRIM24TRIM33TYRCDK1
SCHEMBL17618925 0.83 ERN1 (0.67) ERN1TRIM24TRIM33TYRCDK1
SCHEMBL29559365 0.83 ERN1 (1.00) ERN1TRIM24TRIM33TYR
SCHEMBL120412 0.83 ERN1 (1.00) ERN1TRIM24TRIM33TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120183751-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-07-19 US disclosed
WO-2009072002-A2 BISPHENOLS IN CANCER THERAPY UNIVERSITY OF MANITOBA (US) 2009-06-11 WO disclosed
WO-2009072002-A2 BISPHENOLS IN CANCER THERAPY UNIVERSITY OF MANITOBA (US) 2009-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120183751-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME RER1, SUN2, POLR1G ERN1 2341/4885TRIM24 2662/4885TRIM33 3634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.