Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751828 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4751495 | 0.86 | KMT2A (0.41) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4751496 | 0.86 | KMT2A (0.41) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL2795203 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL2796701 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4751514 | 0.76 | CCR1 (0.48) | — | |
| SCHEMBL4751513 | 0.76 | CCR1 (0.48) | — | |
| SCHEMBL4751929 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9298896 | 0.74 | SMN1; SMN2 (0.67) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL30668842 | 0.74 | SMN1; SMN2 (0.67) | ALDH1A1KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008150231-A1 | NEW HETEROCYCLIC COMPOUNDS FOR TREATMENT OF RESPIRATORY, AIRWAY OR INFLAMMATORY DISORDERS | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008150231-A1 | NEW HETEROCYCLIC COMPOUNDS FOR TREATMENT OF RESPIRATORY, AIRWAY OR INFLAMMATORY DISORDERS | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | WO | disclosed |