Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751495 | 1.00 | KMT2A (0.41) | KMT2AALDH1A1SMN1; SMN2CCR1CYP2D6 | |
| SCHEMBL4751827 | 0.86 | ALDH1A1 (0.49) | KMT2AALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4751828 | 0.86 | ALDH1A1 (0.49) | KMT2AALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4751514 | 0.80 | CCR1 (0.48) | CCR1CYP2D6ALOX15BRD4 | |
| SCHEMBL4751513 | 0.80 | CCR1 (0.48) | CCR1CYP2D6ALOX15BRD4 | |
| SCHEMBL4748912 | 0.73 | ABCB11 (0.47) | KMT2AALDH1A1SMN1; SMN2CCR1KCNH2 | |
| SCHEMBL14301162 | 0.73 | KMT2A (0.49) | KMT2ASMN1; SMN2CYP2D6KCNH2MEN1 | |
| SCHEMBL3676228 | 0.72 | ABCB11 (0.75) | KMT2AALDH1A1CCR1KCNH2MAPT | |
| SCHEMBL4341205 | 0.70 | ALDH1A1 (0.39) | KMT2AALDH1A1CCR1KCNH2MAPT | |
| SCHEMBL7754190 | 0.70 | CA1 (0.51) | KMT2AALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008150231-A1 | NEW HETEROCYCLIC COMPOUNDS FOR TREATMENT OF RESPIRATORY, AIRWAY OR INFLAMMATORY DISORDERS | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | WO | disclosed |