⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105249 | 1.00 | — | — | |
| SCHEMBL346804 | 0.79 | — | — | |
| SCHEMBL68116 | 0.74 | — | — | |
| SCHEMBL11379748 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL11080238 | 0.70 | — | — | |
| SCHEMBL14198852 | 0.67 | — | — | |
| SCHEMBL653873 | 0.67 | ALDH1A1 (0.40) | — | |
| Iodide SCHEMBL3135770 | 0.67 | ALDH1A1 (0.40) | — | |
| SCHEMBL19832276 | 0.67 | — | — | |
| SCHEMBL15167041 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046235-A9 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | claimed |
| EP-1933878-B1 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DE GMBH (DE) | 2012-02-01 | — | — | EP | claimed |
| EP-2279752-A2 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | Fresenius Kabi Deutschland GmbH (DE) | 2011-02-02 | — | — | EP | claimed |
| US-20100311670-A1 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-09 | — | — | US | claimed |
| US-20080207562-A1 | Conjugates of Hydroxyalkyl Starch and Active Substance, Prepared by Chemical Ligation Via Thiazolidine | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | claimed |
| EP-1762250-A1 | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine | Fresenius Kabi Deutschland GmbH (DE) | 2007-03-14 | — | — | EP | claimed |
| US-6011175-A | Inhibition of farnesyltransferase | UNIVERSITY OF PITTSBURGH (US) | 2000-01-04 | — | — | US | claimed |
| US-5965539-A | PEPTIDOMIMETICS; ANTI-CANCER DRUGS | UNIVERISTY OF PITTSBURGH (US) | 1999-10-12 | — | — | US | claimed |
| EP-0794789-A4 | INHIBITORS OF PRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-05-26 | — | — | EP | claimed |
| US-5834434-A | PEPTIDOMIMETICS | UNIVERSITY OF PITTSBURGH (US) | 1998-11-10 | — | — | US | claimed |
| US-5705686-A | 3-MERCAPTO-2-AMINO-PROPYLAMINOBIPHENYL DERIVATIVES; PEPTIDOMIMETICS; ANTICARCINOGENIC AGENTS | UNIVERSITY OF PITTSBURGH (US) | 1998-01-06 | — | — | US | claimed |
| EP-0794789-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-09-17 | — | — | EP | claimed |
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | claimed |
| US-20220179311-A1 | CURABLE COMPOSITION, CURED PRODUCT, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2022-06-09 | — | — | US | disclosed |
| US-20120046235-A9 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-1933878-B1 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DE GMBH (DE) | 2012-02-01 | — | — | EP | disclosed |
| EP-0576915-B1 | cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-derivatives and pharmaceutical compositions comprising same for the treatment of cardiovascular disorders | SIGMA TAU IND FARMACEUTI (IT) | 1997-04-16 | — | — | EP | disclosed |
| US-5593982-A | SUCH AS HEART FAILURE AND HYPERTENSION | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1997-01-14 | — | — | US | disclosed |
| US-5432169-A | Cyclopentanperhydrophenanthren-17β-(3-furyl)-3-derivatives and pharmaceutical compositions comprising same for the treatment of cardiovascular disorders | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1995-07-11 | — | — | US | disclosed |
| EP-0576915-A2 | cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-derivatives and pharmaceutical compositions comprising same for the treatment of cardiovascular disorders | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1994-01-05 | — | — | EP | disclosed |