SCHEMBL653873

SCHEMBL653873

NCC(N)CCC(N)CN

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43273 0.89
SCHEMBL9111058 0.84 ENPEP (0.38) ALDH1A1
SCHEMBL11810443 0.84 ENPEP (0.38) ALDH1A1
SCHEMBL181418 0.84
SCHEMBL12321641 0.83
SCHEMBL20758116 0.83
SCHEMBL20833191 0.83
SCHEMBL1752089 0.83
SCHEMBL12321180 0.83
SCHEMBL1482755 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116367909-A Metal-organic frameworks for carbon dioxide capture 埃克森美孚技术与工程公司 2023-06-30 CN claimed
EP-4132586-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY Tiba Biotech LLC (US) 2023-02-15 EP claimed
US-20230174459-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (US) 2023-06-08 US disclosed
EP-4132586-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY Tiba Biotech LLC (US) 2023-02-15 EP disclosed
WO-2023015204-A1 AGENTS, COMPOSITIONS, AND METHODS FOR CANCER DETECTION THE JOHNS HOPKINS UNIVERSITY (US) 2023-02-09 WO disclosed
US-20200361854-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2020-11-19 US disclosed
US-20200090917-A1 TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND 2020-03-19 US disclosed
US-10347476-B2 Tuned synthetic dendrimer calibrants for mass spectrometry THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2019-07-09 US disclosed
US-10208240-B2 Fluid efficiency and flow back enhancer HALLIBURTON ENERGY SERVICES, INC. (US) 2019-02-19 US disclosed
US-9944534-B2 Reducing aluminosilicate scale in the Bayer process ECOLAB USA INC. (US) 2018-04-17 US disclosed
US-20180065918-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2018-03-08 US disclosed
US-20120046478-A1 LIPID CONTAINING FORMULATIONS ALNYLAM PHARMACEUTICALS, INC. (US) 2012-02-23 US disclosed
US-8119665-B2 Aryl imidazoles and related compounds as C5a receptor modulators NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) 2012-02-21 US disclosed
US-20110269814-A1 2'-F MODIFIED RNA INTERFERENCE AGENTS Alnylam Pharamaceuticals, Inc. (US) 2011-11-03 US disclosed
US-8034376-B2 Lipid containing formulations Alnylam Pharamaceticals, Inc. (US) 2011-10-11 US disclosed
WO-2009142822-A9 2-F MODIFIED RNA INTERFERENCE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2010-01-14 WO disclosed
WO-2009142822-A2 2-F MODIFIED RNA INTERFERENCE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2009-11-26 WO disclosed
EP-2068886-A2 LIPID CONTAINING FORMULATIONS Alnylam Pharmaceuticals Inc. (US) 2009-06-17 EP disclosed
US-20090023673-A1 LIPID CONTAINING FORMULATIONS BANK OF AMERICA, N.A. 2009-01-22 US disclosed
WO-2008042973-A2 LIPID CONTAINING FORMULATIONS ALNYLAM PHARMACEUTICALS, INC. (US) 2008-04-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269814-A1 2'-F MODIFIED RNA INTERFERENCE AGENTS AGO2, NSUN2, XRN2 ALDH1A1 2653/4885
US-20200361854-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 ALDH1A1 3971/4885
US-10347476-B2 Tuned synthetic dendrimer calibrants for mass spectrometry SRMS, SRM, DNMT1 ALDH1A1 3320/4885
US-20180065918-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 ALDH1A1 3971/4885
US-20230174459-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 ALDH1A1 3971/4885
US-20200090917-A1 TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY SRMS, SRM, DNMT1 ALDH1A1 3381/4885
US-20090023673-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 ALDH1A1 3971/4885
US-20120046478-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 ALDH1A1 3971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.