Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LHCGR | P22888 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307502 | 1.00 | HHAT (0.45) | HHATKMT2AMAPK1NPSR1LHCGR | |
| SCHEMBL3307496 | 1.00 | HHAT (0.45) | HHATKMT2AMAPK1NPSR1LHCGR | |
| SCHEMBL4751291 | 0.84 | HHAT (0.38) | HHATMAPK1NPSR1LHCGRGRIN2B | |
| SCHEMBL2994354 | 0.80 | SMN1; SMN2 (0.42) | HHAT | |
| SCHEMBL2994360 | 0.80 | SMN1; SMN2 (0.42) | HHAT | |
| SCHEMBL2994358 | 0.80 | SMN1; SMN2 (0.42) | HHAT | |
| SCHEMBL3302736 | 0.80 | HHAT (0.44) | HHATKMT2AMAPK1NPSR1LHCGR | |
| SCHEMBL2836823 | 0.76 | DRD1 (0.41) | HHATKMT2AMAPK1NPSR1GRIN2B | |
| SCHEMBL19722754 | 0.73 | NPC1 (0.38) | HHATMAPK1NPSR1GRIN2B | |
| SCHEMBL14970374 | 0.73 | HHAT (0.43) | HHATMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |