Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748892 | 0.91 | KDM4E (0.37) | ALDH1A1KDM4EHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL4748891 | 0.91 | KDM4E (0.37) | ALDH1A1KDM4EHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3308515 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDL3MBTL1RAB9A | |
| SCHEMBL3307455 | 0.80 | HPGD (0.40) | ALDH1A1KDM4EHPGDL3MBTL1RAB9A | |
| SCHEMBL4751943 | 0.77 | DRD1 (0.34) | MAPK1CYP1A2HSD17B10TSHRLMNA | |
| SCHEMBL3309479 | 0.76 | KDM4E (0.54) | ALDH1A1KDM4EHPGDL3MBTL1RAB9A | |
| SCHEMBL3304805 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1174522 | 0.74 | HDAC6 (0.53) | ALDH1A1KDM4EHPGDL3MBTL1RAB9A | |
| SCHEMBL3307517 | 0.73 | KDM4E (0.40) | ALDH1A1KDM4EHPGDL3MBTL1RAB9A | |
| SCHEMBL13550058 | 0.73 | KDM4E (0.52) | ALDH1A1KDM4EHPGDL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |